Assistant Professor of Hematology, Department of Medical Laboratory Sciences, Faculty of Paramedicine, Hamedan University of Medical Sciences, Hamedan, Iran , rafee_1352@yahoo.com
                    
                    
                    Abstract:       (28472 Views)
                    
                    
                    Abstract
Background and Objective: Glutathione as a master antioxidant plays a key role in eliminating free radicals from your body and in preserving cell membrane integrity esp. blood cells. We aimed to assess the Erythrocyte Glutathione level of favism and non-favism neonates.
Material and Methods:  This study was conducted in Ekbatan hospitals of Hamadan (2009) on 15 favism patients and 60 non-favism ones matched by sex and age.  Using Beutler method, the reduced Glutathione (GSH) level of red blood cells was measured. 
Results:  Based on the results, the amount of erythrocyte GSH in favism patients was 14.99±4.62 mg/dl and that of controls was 58.2±10.59 mg/dl.
Conclusion:  the results show that the erythrocyte GSH in favism patients is significantly lower than that of non-favism subjects therefore, the former seems more likely to be afflicted by hemolytic crises owing to the use of   oxidant stuff.  
Keywords: Favism Glutathone Neonates G6PD
                    
                    
                    
                    
                    
                    Research Article:  
Original Paper |
                    
                      
Received: 2013/09/11 | Accepted: 2013/10/29 | Published: 2013/10/29 | ePublished: 2013/10/29